Clinical Course (> 12 h) Iss Calculator Clinical Course Hemorrhage Need for catecholamines No Yes Lactate > 2 mmol/L No Yes Urine production < 1ml/kg/h No Yes Increasing systemic inflammatory response No Yes Coagulopathy Platelet count (μg/ml)< 90.000 No Yes Any signs of coagulopathy or disseminated intravasal coagulopathy (DIC) No Yes Hyperthermia Temperature > 38°C No Yes Soft Tissue Injuries Brain swelling, GCS ≤8 No Yes Lung function; PaO2/FiO2 350 - 400 < 350 Abdominal Compartment, Ileus No Yes Rhabdomyolysis, Soft tissue swelling, Blisters, Soft Tissue Defects No Yes Finish Recommendation
